At one point the narrator says, "Bill went home and masturbated for 7 hours."

A few other references to people's crotches are made. In one shot, the crotch bulges look ridiculously bloated and rather large (however it isn't anatomically correct at all).

A very brief mention of Asian porn in a magazine.

A very brief mention that Bill's testicle has an ache in it.

There's a scene in which the main character watches a boxing match on TV, which depicts a man getting his head graphically and bloodily split open. This scene is then replayed several times.

References are made to death and murder, including people getting run over by trains (non-graphic), and getting objects thrown at them, or bludgeoned (again, non-graphic).

A mentally and physically disabled child is said to have been suffocated by another person.

Three animated horse carcasses are shown

All violence is animated and although some of it is graphic, it isn't visually detailed.

Some mild profanities such as "hell," "damn," and "goddamn."

Characters take prescription medication, but there are incidents of misuse or missing doses.

The movie is about a man slowly succumbing to a brain tumor that he has. The film's tone is rather sentimental and depressing in parts.

Several very surreal dream sequences and hallucinations from the main character. One dream includes a giant fish that supposedly grows on the main character's head.

Photosensitive viewers may have a hard time watching due to bright, flashing lights and rapid patterns within the film.

The ending is highly emotional and may be too heavy for some viewers.