Frequent cigarette smoking.
Two men have a lengthy discussion about how hash is legal in Amsterdam.
A man buys heroin from his friend. He then describes how the heroin makes you high, when you use it, where it comes from and how much it costs.
One man briefly smokes marijuana using a joint and a woman uses a bong.
Some casual drinking.
A woman uses a credit card to get some cocaine ready to snort however the use of the drug is not shown but implied.
A woman goes into a bathroom and puts her head down (off camera) and we hear her snorting something (cocaine) there are several other women doing the same thing, she then pulls her head up and has a bit of cocaine underneath her nose which she wipes.
Occasional drug references from the protagonists.
Almost all of the drug use ends up backfiring against whoever uses it. The drug use though is very explicit, especially the heroin scene which is shown in extremely graphic detail and for an extended period of time.
A man graphically prepares and injects heroin and a woman mistakes it for cocaine and snorts some. She collapses and nearly dies before getting an adrenaline shot to the heart.
Many uses of drugs throughout the first hour of the film.
Multiple onscreen drug uses.