The two main characters have sex with each other, but it's not very explicit.

There are at least two instances where a character fails to have sex with another character.

Some other references.

There is lots of strong language. Plenty of fucks and some uses of cocksucker. There is also other mild language such as hell, damn, goddamn, shit and asshole for example.

Some drug references and people drinking.

Some scenes are intense, but the movie is very comical in nature.