Medusa is shown to be physically, verbally, and psychologically abusive towards her partner, Penny, and her pet alligators
Some reckless driving and gun shooting by Medusa. She narrowly misses shooting people. She points her gun at Snoops and Penny towards the end and threatens to blast them. Definitely not a responsible gun owner
Medusa nearly crashes into a parked pickup truck while speeding through the downtown streets, but switches lanes to avoid a collision.
Medusa nearly crushes Bianca who's under the gas pedal, but the latter manages to escape.
Upon first spotting the two mice, Medusa freaks and blasts violently at them with a shotgun (the two mice narrowly manage to escape).
In the climax, Medusa uses her shotgun attempt to try and shoot Penny. After she misses, she tries firing again, but the bayou critters load a stick of dynamite in her shotgun, literally causing the plan to blow up in her face (she is otherwise unharmed, though).
A swamp critter stabs Medusa in the butt with a pitchfork in one scene, causing her to scream (played for laughs).