The film contains some verbal references to sex.

Man and women kiss, she implies she enjoyed having sex with him earlier (no sex scenes or nudity in the movie, only dialogue).

A man and woman have intercourse offscreen.

This movie is quite violent but the main issue is the depressing thematic material throughout.

A woman kicks two high schoolers (one boy, one girl) hard in their crotches.

A man throws an IV of blood against a wall resulting in a small bloody splash.

A man suffering from cancer coughs some small spots of blood onto a woman's face by accident.

We briefly see photos of a severely burned corpse of a murder victim.

Graphic references to sexual assault.

A police officer beats up a man with a pistol and tosses him out of a window while some woman in the building is screaming in anger. The police officer punches the screaming woman in the face.

Non-stop swearing throughout. 100 uses of "fuck"; a few of the uses are sexual. 2 uses of "cock"; both are used in a sexual manner. 4 uses of "cunt". Use of homophobic and racial slurs. A few uses of "shit", "bitch", "retard", and "asshole" are present as well.

The film contains some verbal references to illegal drug possession.

Drinking and smoking regularly throughout the film.

Someone asks Mildred if she has done drunk driving; she says, "Maybe once."

This film is very heavy. It revolves around a woman who lost her daughter to a rapist and it is mentioned that she was burned alive. She then decides to put up Billboards that say the police aren't doing their jobs, which drives the whole town into anger, and hatred. Other dark elements are explored such as a man dying of cancer, suffering from the loss of a child, rape, domestic abuse, depression, onscreen depiction of suicide and violence.

A woman drills a tiny hole through a man's nail in self-defense.

The film has many moments that are played for dark humor, but are still intense.