It's implied that a child is being sexually abused.

A child is routinely abused by her mother and her mother's boyfriend. The injuries (bruises, burn marks, etc.) on her body are seen multiple times.

Some scenes set in a bar where alcohol is clearly seen.

Smoking in some episodes.

The plot concerns a teacher who goes on the run with her elementary school student, whom she kidnaps from her abusive mother. There are plenty of emotional scenes dealing with child abuse, child murder and neglect that most viewers will find distressing.