There is at least one woman who shows fully exposed breasts.

Episode called Touched By An ET, a real woman's breast is shown.

Episode called It's My Party, a woman's buttcrack is shown.

A few episodes contain implied nudity and, occasionally, mild sexual behavior.

Realistically graphic (and sometimes very gory) pranks are depicted, but keep in mind that it's all fake.

Bleeped-out (but generally frequent) profanities

Some drinking and smoking

Some of the pranks pulled on people in the show are very frightening in nature.