Characters discuss sex, infidelity, promiscuity, homosexuality, transsexuality, and masturbation between each other, sometimes in a medical context (this occasionally involves teens and children) or casually. These conversations are not graphic and at times comical. Prostitution is also mentioned as many patients (men and women, who are at times adolescents and even children) are said to be prostitutes.

Characters are occasionally seen kissing and making out

Characters flirt with each other throughout the show, this occasionally includes sexual innuendos

Medical procedures are done on certain patients' genitalia throughout the show. Nothing is ever seen other than the doctor's arms being in between the patient's legs or pictures being taken. This includes circumcisions, rape kit exams (at times done on cadavers and unconscious patients), pap smears, recovery of items stuck inside patients, abortions, and births. This sometimes involves teens and children. Pubic hair, ejaculation, penetration, erections, semen, and impotency are mentioned. Doctors sometimes go into detail and describe what is being done in medical terms.

There are scenes where sex is implied. For example, characters are seen next to each other in bed or kissing each other and undressing before the scene cuts away.

There are occasional sex scenes throughout, characters are sometimes heard moaning & panting (at times loudly and off-screen) and they are seen moving under some sheets and kissing each other. These scenes are usually brief and not graphic, at times we see the bare buttocks of some characters when getting out of bed, a woman's bare back, or the side of a woman's boobs. In some extremely rare instances, we see a woman's bare breasts, but very briefly and hard to see. Although some seasons don't have any sex scenes at all, some have multiple.

Male & female rear nudity is seen throughout the show, sometimes in a medical context or sexual context (characters getting out of bed after intercourse). This is usually brief, although there are some close-up shots in a few episodes.

STDs are mentioned and discussed throughout the show, some characters contract them. Methods of contraception and practicing safe sex are usually mentioned in these conversations, this sometimes involves teens.

Men are sometimes seen in their underwear and women are also occasionally seen in their bra & panties or lingerie

Some women throughout the show are braless and their nipples can briefly be seen poking through their shirts.

We clearly see the bare breasts of a woman in ONE episode throughout the show. This is an elderly woman, in a medical context and it is brief.

Some men are seen air humping, touching themselves, and masturbating. This is extremely rare and usually very brief, hand movements are seen under sheets or they are seen grabbing their crotch. The term "jerking off" is sometimes used

A close-up of a man scratching his bulge in an episode. A man with an erection through his boxers is seen in another.

Dildos and vibrators are very briefly seen (also heard) and discussed in some episodes. Inflatable dolls are also seen in a few episodes. Some patients are seen coming in leather gimp suits.

Characters are seen watching pornography in an episode in one of the last seasons, we only hear the audio of a man and a woman moaning loudly and talking sexually (telling the man to spank her)

Pedophilia is discussed pretty graphically in some episodes. A few patients throughout the show are pedophiles, in one episode a man is seen following a child inside a bathroom and in another, a man is seen grooming children.

Many characters are victims of rape, this is sometimes described pretty graphically as the victims are questioned. The victims are at times teenagers and elderly people. Some episodes also involve the sexual abuse of children and rape kit exams are done on them too. There are a series of episodes which revolve around a serial rapist.

Some patients lose their limbs in accidents and the limb is seen separated from the body. The camera does not focus too long on the gory details.

Throughout the show, we see characters with a wide range of injuries and medical conditions. Some are covered in blood, some with cuts, burns, bruises, large wounds, broken bones (at times sticking out of the skin), and impaled with objects. The patients are occasionally children and teens. The show doesn't linger too long on the graphic details and usually focuses on the doctors instead of the injuries. Incisions are sometimes performed on screen, although this is very rare and when it does happen, it is brief.

There are scenes where characters try to commit suicide or successfully commit suicide, at times done on screen. Characters ingest drugs, shoot themselves, jump off buildings, cut themselves, hang themselves and self-immolate. This is mostly mentioned instead of shown.

Patients are frequently seen getting stitches throughout the show, this is usually not very graphic.

We see victims of child abuse and domestic violence in many episodes, characters are seen with injuries such as cuts, burns and bruises.

In many scenes blood is seen on the doctors' hands and on their uniforms while they are operating on patients. Blood squirts from wounds and pools of blood are seen. Numerous patients are seen vomiting blood.

There are occasional fistfights between characters, patients are sometimes violent and need restraining. Punching, pushing, kicking, biting, slapping, tackling, and sometimes choking is seen. Some of these scenes are quite intense.

Murder is the subject of certain episodes, some patients are victims of shootings and stabbings, these are sometimes children. They are seen on-screen in some episodes, characters are seen pointing guns at people, being in gunfights, getting stabbed, getting pistol-whipped, and getting shot.

A pretty brutal scene happens in the last season where a man is repeatedly punched in the face on-screen which leaves him disfigured and in a very bloody state. One of the most violent scenes throughout the series

Moderately graphic medical detail

There are a some uses of "Damn"

"Bitch", "Son of a Bitch", "Whore" and "Slut" are used in some episodes

"Prick" and "Bastard" are used in some episodes

The N-word in a racist context and "Spic" are used in some episodes

Some characters are seen giving the middle finger

Some characters are called "jerkoffs"

"Faggot" and "Dyke" are used in some episodes

1 use of "Shit" in an episode and 1 use of "Shitty" in another

"Ass" is occasionally used and "tits" is used on some rare occasions

Adults, teens and children overdose on prescription drugs and illegal drugs throughout the show.

There are some episodes that are about people getting injured due to drunk driving yet no actual alcohol is shown in these scenes.

Certain episodes revolve around patients who have taken illegal drugs and are seen high.

Characters are sometimes seen smoking cigarettes (including pregnant women) throughout the show. The negative affects of smoking tobacco arementioned frequently. Some of the main characters struggle with nicotine addiction.

Many characters are seen drinking alcohol and being inebriated and at times blacking out throughout the show. The blood alcohol levels of patients are discussed in many episodes. Some characters (including main characters) are alcoholics and the effects of alcoholism are talked about.

Drug smuggling and drug dealing are mentioned and seen. This sometimes involves children and is the subject of certain episodes.

Many characters are drug addicts, they are sometimes called junkies. Some are seen injecting themselves with syringes, smoking and snorting on screen in certain episodes. Characters are also seen detoxing and going through withdrawals. Characters relapse and also go to rehab.

Many patients fake symptoms because they are drug seeking. This happens numerous times throughout the show.

Characters are seen smoking marijuana in some episodes, the medical benefits are also discussed. There is one pretty extensive scene where a nurse smokes a marijuana joint and blows the smoke into a patient's mouth as he says it relieves pain.

Cocaine, heroin, acid, meth and marijuana are seen and/or mentioned.

The whole show is incredibly intense, fast-paced and unpredictable, with some patients coming into the hospital in a very bloody state and sometimes with missing limbs. We see certain characters have seizures and heart attacks. Some of the patients are in unbearable pain and are seen screaming. Certain episodes have a very somber tone to them and might be harder to watch for some viewers. It's very realistic (even if it becomes move over-the-top in later seasons), and very intense.

Some episodes are upsetting and deal with quite depressing and dark subjects such as suicide, cancer (sometimes children with cancer), STDs (including AIDs), rape, infidelity, poverty, miscarriages, murder (sometimes of children and teens), drug addiction & alcoholism, stalking & harassment (characters are stalked over the period of many episodes), child abuse, abortions, mental illnesses, divorce, mental disorders (depression, schizophrenia, eating disorders, PTSD), racism, domestic violence, and death.

Many characters (children and adults) are seen dying, sometimes onscreen and also offscreen (almost every episode includes a death). Some of these scenes are very intense, we often see how this affects the person's friends and loved ones. These scenes might be upsetting for some viewers.